MicroRNAs (miRNAs) are a Canvas Prints class of noncoding RNAs that negatively regulate target messenger RNAs.In multicellular eukaryotes, numerous miRNAs perform basic cellular functions, including cell proliferation, differentiation, and death.Abnormal expression of miRNAs weakens or modifies various apoptosis pathways, leading to the development
Realizing effective enhancement to the Canvas Prints structure of interface region between explosive crystals and polymer binder plays a key role in improving the mechanical properties of the current polymer bonded explosives (PBXs).Herein, inspired by the structure of natural nacre which possesses outstanding mechanical performance, a kind of nacr
Intrinsic apoptosis, the response to intracellular cell death stimuli, is regulated by the interplay of the B-cell lymphoma 2 (Bcl-2) family and their membrane interactions.Bcl-2 proteins mediate a number of processes including development, homeostasis, autophagy, and innate and adaptive immune responses and their dysregulation underpins a host of
Background Scar visibility is a major deterrent to patients seeking reconstructive surgery.Endoscopic surgery can address a wide range of problems, from minimizing or concealing scars to improving access and outcomes in certain situations.This case series includes a wide range of reconstructive surgery problems addressed by subcutaneous endoscopic
Membrane lipids extensively modulate the activation gating of voltage-gated potassium channels Iron (KV), however, much less is known about the mechanisms of ceramide and glucosylceramide actions including which structural element is the main intramolecular target and whether there is any contribution of indirect, membrane biophysics-related mechan